What is omeprazole, and how does it work (mechanism of action)?
Omeprazole is in a class of drugs called
proton pump inhibitors (PPI) that block the production of acid by the stomach.
Other drugs in the class include lansoprazole (Prevacid), rabeprazole (Aciphex),
pantoprazole (Protonix), and esomeprazole (Nexium). Proton pump inhibitors are
used for the treatment of conditions such as ulcers, gastroesophageal reflux
disease (GERD) and the Zollinger-Ellison
syndrome, which are all caused by
stomach acid. Omeprazole, like other proton-pump inhibitors, blocks the enzyme
in the wall of the stomach that produces acid. By blocking the enzyme, the
production of acid is decreased, and this allows the stomach and esophagus to
heal. Zegerid contains omeprazole and an antacid (sodium bicarbonate). The FDA
approved omeprazole in September 1989.
What brand names are available for omeprazole?
Prilosec, Zegerid, Prilosec OTC, Zegerid OTC
Is omeprazole available as a generic drug?
Yes (Prilosec)