The medication was first introduced to the American market by Eli Lilly in 1988. Within a few years of being approved by the Food and Drug Administration (FDA), Prozac became one of the most widely prescribed antidepressants in the country.
It works by blocking the absorption of the neurotransmitter serotonin in the brain. Regulating the amount of serotonin helps brain cells transmit messages to each other, resulting in a better and more stable mood.
Prozac is commonly prescribed on its own, but can also be used combination with olanzapine (Zyprexa) to treat manic depression for patients with bipolar disorder; fluoxetine combined with olanzapine is known as Symbyax.
Even though there are newer SSRIs like sertraline and citalopram, Prozac is still one of the most popular antidepressants available.
The drug is available as a liquid, tablet, capsule, and as a delayed-release (long-acting) capsule.
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